- Heightened Risk of Postoperative Delirium and Cognitive Decline: In patients aged 70 and older with Alzheimer’s, pre-existing cognitive impairment significantly increases the likelihood of postoperative delirium or worsened mental status following sedation, necessitating preoperative cognitive assessment and multidisciplinary planning to mitigate risks.
- Dose Adjustment for Sedatives: Elderly patients require lower doses of agents like midazolam for IV sedation to achieve adequate effect without excessive cognitive impact, as higher doses can prolong recovery and contribute to mental status alterations.
- Avoidance of Benzodiazepines and Anticholinergics: These medications should be minimized or avoided in geriatric patients over 70 with dementia, as they can exacerbate confusion, delirium, or long-term cognitive changes during oral or IV sedation for dental procedures.
- Perioperative Monitoring for Mental Status Changes: Continuous assessment of cognitive function is essential before, during, and after sedation in older adults, with prompt intervention for any emerging delirium, especially given the potential for delayed recovery lasting hours to weeks.
- Selection of Sedation Modality: For patients 70+ with Alzheimer’s, consider alternatives like inhalation sedation (e.g., nitrous oxide or sevoflurane) over IV options if feasible, to reduce anxiety and procedural stress while minimizing risks to mental status compared to deeper sedation methods.

Top 5 Anesthetic Considerations for a Patient with Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease increases anesthetic risk during dental procedures due to limited respiratory reserve and sensitivity to sedatives. This article outlines five key considerations to support safe sedation, oxygen management, and respiratory monitoring.
